Glossary

PDRN

Also known as: Polydeoxyribonucleotide, sodium DNA, salmon DNA

In short

PDRN (polydeoxyribonucleotide) is a purified fragment of DNA, usually from salmon, used in Korean skincare to help skin look and feel hydrated, smooth and bouncy. On ingredient lists it appears as sodium DNA.

Where does PDRN come from?

Most PDRN in skincare comes from salmon. The DNA is purified to remove proteins and fats, leaving short fragments that can go into balms, serums and creams. Because it comes from fish, skincare with salmon PDRN is not vegan.

What does PDRN do in skincare?

Applied to the skin, PDRN is there for how skin looks and feels: more hydrated, softer and smoother, with fine lines that look less visible. It first became known through injectable treatments in clinics, which are medical procedures and quite different from skincare.

How do you find PDRN on a label?

Look for sodium DNA in the ingredient list. Brands usually write PDRN or salmon DNA on the front of the pack.

For the full story, read our guide What is PDRN in skincare?

Where you'll find it

Multi-useWrinkle Bounce Multi Balm 4.7 (507)

Face, eyes, smile lines, lips and neck

£24.99

See the full ingredients
Eye careEye Balm 4.8 (214)

A lighter formula for the eye area

£24.99

See the full ingredients
EssenceSkin Fit Blending Essence

A silky capsule essence that melts into skin

£32.99

See the full ingredients
Sheet maskWater Full Face Mask

Six soaked cotton sheet masks, one a week

£27.99

See the full ingredients

Frequently asked questions

Is PDRN vegan?

No. PDRN in skincare usually comes from salmon, so it is not vegan. If you have a fish allergy, check with your GP or pharmacist before use.

Is PDRN skincare the same as a salmon DNA facial?

No. Salmon DNA facials use injectable PDRN and are carried out by medical professionals. Skincare applies PDRN to the surface of the skin, for how it looks and feels.

Sources and references

  1. Pharmacological activity and clinical use of PDRN. Squadrito F. et al., Frontiers in Pharmacology, 2017.
  2. CosIng database of cosmetic ingredients: Sodium DNA. European Commission.